DOI: https://dx.doi.org/10.18203/2394-6040.ijcmph20214838
Published: 2021-12-27

Serological co-infection of dengue and COVID-19: case series in Bangladesh

Tahmina Zahan, Morshed Nasir, Afzal Akhtar, A. F. M. Mohibur Rahman, Tanha E. Nahin

Abstract


Parallel symptoms and laboratory findings between dengue and coronavirus disease 2019 (COVID-19) pretense a diagnostic contest in some dengue-endemic countries in Asia. In this study, we described ten cases of suspected COVID-19-dengue co-infection in a tertiary care hospital in Bangladesh. Serological data showed that patients with positive results for dengue virus (DENV) NS1 antigen and anti-dengue IgG and IgM were also reactive to COVID-19 rapid antibody tests, suggesting dengue with COVID-19 coinfection. The present study indicated a public health concern regarding COVID-19 and dengue detection in Bangladesh as well as in other dengue-endemic countries and it was important for these nations to manage both pathogens concurrently.


Keywords


Dengue, COVID-19, Co-infection, Bangladesh

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References


Bai Y, Yao L, Wei T, Tian F, Jin DY, Chen L, et al. Presumed asymptomatic carrier transmission of COVID-19. JAMA. 2020;323(14):1406-7.

Blacksell SD, Jarman RG, Bailey MS, Tanganuchitcharnchai A, Jenjaroen K, Gibbons RV, et al. Evaluation of six commercial point-of-care tests for diagnosis of acute dengue infections: the need for combining NS1 antigen and IgM/IgG antibody detection to achieve acceptable levels of accuracy. Clin Vaccine Immunol. 2011;18(12):2095-101.

Criado PR, Pagliari C, Carneiro FRO, Quaresma JAS. Lessons from dermatology about inflammatory responses in COVID-19. Rev Med Virol. 2020;30(5):2130.

Deeks JJ, Dinnes J, Takwoingi Y, Davenport C, Spijker R, Taylor-Phillips S, et al. Cochrane COVID-19 diagnostic test accuracy group. antibody tests for identification of current and past infection with SARS-CoV-2. Cochrane Database Syst Rev. 2020;6(6):013652.

Epelboin L, Blondé R, Nacher M, Combe P, Collet L. COVID-19 and dengue co-infection in a returning traveller. J Travel Med. 2020;27(6):114.

Frediansyah A, Tiwari R, Khan S, Dhama K, Harapan H. Clinical epidemiology and global health. Clinical Epidemiol Glob Health. 2020;9(2).

Harapan H, Itoh N, Yufika A, Winardi W, Keam S, Te H, et al. Coronavirus disease 2019 (COVID-19): a literature review. J Infect Public Health. 2020;13(5):667-73.

Harapan H, Ryan M, Yohan B, Abidin RS, Nainu F, Rakib A, et al. COVID-19 and dengue: double punches for dengue-endemic countries in Asia. Rev Med Virol. 2021;31(2):2161.

Henrina J, Putra ICS, Lawrensia S, Handoyono QF, Cahyadi A. Coronavirus disease of 2019: a mimicker of dengue infection? SN Compr Clin Med. 2020:1-11.

Kembuan GJ. Dengue serology in Indonesian COVID-19 patients: coinfection or serological overlap? ID Cases. 2020;22:00927.

Lustig Y, Keler S, Kolodny R, Ben-Tal N, Atias-Varon D, Shlush E, et al. Potential antigenic cross-reactivity between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and dengue viruses. Clin Infect Dis. 2021;73(7):2444-9.

Miah MA, Husna A. Coinfection, coepidemics of COVID-19, and dengue in dengue-endemic countries: a serious health concern. J Med Virol. 2021;93(1):161-2.

Prasitsirikul W, Pongpirul K, Pongpirul WA, Panitantum N, Ratnarathon AC, Hemachudha T. Nurse infected with Covid-19 from a provisional dengue patient. Emerg Microbes Infect. 2020;9(1):1354-5.

Saddique A, Rana MS, Alam MM, Ikram A, Usman M, Salman M, et al. Emergence of co-infection of COVID-19 and dengue: a serious public health threat. J Infect. 2020;81(6):16-8.

Spinicci M, Bartoloni A, Mantella A, Zammarchi L, Rossolini GM, Antonelli A. Low risk of serological cross-reactivity between dengue and COVID-19. Mem Inst Oswaldo Cruz. 2020;115:200225.

Verduyn M, Allou N, Gazaille V, Andre M, Desroche T, Jaffar MC, et al. Co-infection of dengue and COVID-19: a case report. PLoS Negl Trop Dis. 2020;14(8):0008476.

Yan G, Lee CK, Lam LTM, Yan B, Chua YX, Lim AYN, et al. Covert COVID-19 and false-positive dengue serology in Singapore. Lancet Infect Dis. 2020;20(5):536.