Quality of life in gynaecologic cancer subjects attending a tertiary care centre

Ranjini Nanjaiah, Roopadevi V., Mudassir A. Khan


Background: As newer treatment modalities improve survival; quality of life issues takes on increasing importance for survivors. An adequate knowledge is required for psychosocial interventions and designing programs aimed at improving the quality of life of the cancer patients. The purpose of the study is to assess quality of life among gynaecological cancer subjects and its association with duration since diagnosis, type of cancer, mode of treatment and socio-demographic variables.

Methods: This is an interview based cross sectional study involving 131 patients diagnosed to have gynaecological cancer who were evaluated using WHOQOL-BREF Questionnaire. The gynaecological and socio-demographic data was analysed for any significant difference in QOL scores using one-way ANOVA.

Results: Social domain scored high with median score 50 ± 22.82. Environmental domain scored least with median score 28 ± 24.91. Based on domain scores it was found that only 2.3% subjects had better quality of life. Physical (55.7 ± 7.43) and psychological (57.95 ± 22.85) domain mean score was statistically significantly higher among subjects with cancer for more than 12 months. Subjects who had radiotherapy and chemotherapy scored least (44.52 ± 9.8) and subjects who had surgery and chemotherapy scored highest (59.43 ± 8.8) in physical domain.

Conclusions: As cancer incidence is increasing and post treatment survival is improving among cancer patients, two factors are gaining importance. One is early detection and prevention of cancer and the other is improving quality of life of survivors. In clinical practice the QOL instruments may be used with other forms of assessment, giving valuable information that can indicate areas in which a person is most affected and help the practitioner in making the best choices in patient care.


Gynaecological cancer, Quality of life, WHOQOL-BREF

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Padubidri VG, Daftary SN. Shaw’s Textbook of Gynecology. 15th edition. Pennsylvania: Elsevier; 2013.

Department of Epidemiology and Biostatistics (Hospital Based Cancer Registry). Kidwai Memorial Institute of Oncology. Available at: Accessed on 3 March 2017.

Kushwaha AS. Maternal and Child Health. In: Vaidya R, Tilak R, Gupta R, Kunte R, eds. Text Book of Public Health and Community Medicine. 1st ed, Dept of Community Medicine, AFMC, Pune; 2009: 809-877.

Chaturvedi SK. Psychiatric oncology: cancer in mind. Indian J Psychiatry 2012;54:111-8.

Shape, M. Stronge, V. Allen, Major Depression in out-patients attending a regional cancer centre, screening and unmet treatment needs. British J Cancer. 2004;90:314-8.

Fernandes WC, Kimura M. Health Related Quality of Life of Woman with cervical cancer. Rev Lat Am Enfermagem. 2010;18(3):360-7.

Development of the World Health Organization WHOQOL-BREF quality of life assessment. The WHOQOL Group. Psychol Med. 1998,28:551-8.

Pearman T. Quality of life and psychosocial adjustment in gynecologic cancer survivors. Health Qual Life Outcomes. 2003;1:33.

Goker A, Guvenal T, Yanikkerem E, Turhan A, Koyuncu FM. Quality of life in women with gynecologic cancer in Turkey. Asian Pac J Cancer Prev. 2011;12(11):3121-8.

Kannan G, Rani V, Ananthanarayanan RM, Palani T, Nigam N, Janardhan V, et al. Assessment of quality of life of cancer patients in a tertiary care hospital of South India. J Cancer Res Ther. 2011;7(3):275-9.

Lutgendorf SK1, Anderson B, Ullrich P, Johnsen EL, Buller RE, Sood AK, et al. Quality of Life and Mood in Women with Gynecologic Cancer A One Year Prospective Study. Cancer. 2002;94(1):131-40.

Ferreira VA, Silveira INT, Gomes NS, Ruiz MT, Silva SR. Quality of life of women with gynecologic and breast cancer undergoing chemotherapy. Rev Rene. 2015;16(2):266-74.

Ries LAG, Kosary CL, Hankey BF, Miller BA, Edwards BK. SEER Cancer Statistics Review, 1973-1995. National Cancer Institute. Bethesda, MD, 1998.

Capelli G, De Vincenzo RI, Addamo A, Bartolozzi F, Braggio N, Scambia G. Which dimensions of health-related quality of life are altered in patients attending the different gynecologic oncology health care settings? Cancer. 2002;95(12):2500-7.

Wilailak S, Lertkhachonsuk AA, Lohacharoen-vanich N, Luengsukcharoen SC, Jirajaras M, Likitanasombat P, et al. Quality of life in gynecologic cancer survivors compared to healthy check-up women. J Gynecol Oncol. 2011;22(2):103-9.

Wenzel LB, Donnelly JP, Fowler JM, Habbal R, Taylor TH, Aziz N, et al. Resilience, reflection, and residual stress in ovarian cancer survivorship: a gynecologic oncology group study. Psychooncol. 2002;11(2):142-53.

Miller BE, Pittman B, Case D, McQuellon RP. Quality of life after treatment for gynecologic malignancies: a pilot study in an outpatient clinic. Gynecol Oncol. 2002;87:178-84.

Chan YM, Ngan HYS, Li BYG, Yip AMW, Ng TY, Lee PWH, et al. A longitudinal study on quality of life after gynecologic cancer treatment. Gynecol Oncol. 2001;83:10-9.

Greimel E, Thiel I, Peintinger F, Cegnar I, Pongratz E. Prospective assessment of quality of life of female cancer patients. Gynecol Oncol. 2002;85:140-7.

Lutgendorf SK, Anderson B, Rothrock N, Buller RE, Sood AK, Sorosky JI. Quality of life and mood in women receiving extensive chemotherapy for gynecologic cancer. Cancer. 2000;89(6):1402-11.

Bodurka-Bevers D, Basen-Engquist K, Carmack CL, Fitzgerald MA, Wolf JK, de Moor C, et al. Depression, anxiety, and quality of life in patients with epithelial ovarian cancer. Gynecol Oncol. 2000;78:302–8.